Using the Horn of Africa as an example, the maps illustrate different steps in a methodology developed to estimate and map the economic benefits to livestock keepers of controlling a disease (Shaw et al. 2014). Cattle are first assigned to different production systems as shown in Map 1, illustrating for example, where mixed farming is heavily dependent on the use of draft oxen in Ethiopia, areas of Sudan and South Sudan where oxen use is much lower, and the strictly pastoral areas of Somalia and Kenya. Information on the location of cattle and production systems is combined with the distribution of tsetse fly species in the area (Map 2) to estimate the presence and absence of trypanosomosis, a parasitic disease transmitted by the tsetse fly. Herd growth and spread is modelled for the current situation, and for the simulated removal of trypanosomosis.