Adding small quantity lipid-based nutrient supplements to an enhanced homestead food production program improves child hemoglobin, iron and vitamin A status in rural Burkina Faso: A cluster randomized controlled trial
Background
Enhanced homestead food production programs (EHFP) including nutrition behavior change communication and women’s empowerment activities have limited impacts on child nutrition. This may be due to short program duration or the absence of interventions to improve water, sanitation, and hygiene (WASH) and access to nutritious foods.
Objective
We assessed impacts on child anemia, micronutrient status and anthropometry of prior village exposure to an EHFP, and of adding WASH alone or WASH with daily small quantity-lipid based nutrient supplements (SQ-LNS).
Design
This 2y longitudinal cluster-randomized controlled trial (2014-2016) included 60 villages in Burkina Faso randomized to four groups (15 per group): (1) EHFP-2014, (2) EHFP-2014+WASH, (3) EHFP-2010+WASH, and (4) EHFP-2010+WASH+SQ-LNS. Groups 3 and 4 had previously received EHFP (2010-2012). We assessed impacts on child anemia and micronutrient status (n=1,704; 3-12.9 mo at baseline) and anthropometry (n=2,308; 0-12.9 mo at baseline) using difference-in-difference (DID) specifications. We controlled for covariates, adjusted for clustering, and assessed interactive effects by child age at baseline. The trial was registered with clinicaltrials.gov (NCT02236468).
Results
We found no impact of prior exposure to EHFP (groups 2 vs 3) on the outcomes examined. Adding WASH (groups 1 vs 2) reduced anemia (hemoglobin (Hb)<11 g/dL) (DID=9.43 pp, p<0.01) and led to a decline in weight-for-age Z-score (WAZ) (DID -0.11±0.04, p=0.01). Adding SQ-LNS (groups 3 vs 4) increased Hb (DID=0.26±0.13 g/dL, p<0.05), plasma ferritin (DID=7.61±2.69 μg/L, p<0.01), and retinol binding protein (DID=0.07±0.02 umol/L, p<0.01) concentrations. Effects were larger in children <6 mo at baseline, where providing SQ-LNS (>6 mo) positively impacted Hb, plasma ferritin, height-for-age Z-score, WAZ, and underweight.
Conclusions
Using EHFP to deliver WASH and SQ-LNS reduced child anemia and improved micronutrient status. Anthropometric improvements were found in children who joined the program before 6 mo of age and were exposed for the whole complementary feeding period.
Authors
Bliznashka, Lilia; Becquey, Elodie; Ruel, Marie T.; Pedehombga, Abdoulaye; Nordhagen, Stella; Olney, Deanna K.
Citation
Bliznashka, Lilia; Becquey, Elodie; Ruel, Marie T.; Pedehombga, Abdoulaye; Nordhagen, Stella; and Olney, Deanna K. 2026. Adding small quantity lipid-based nutrient supplements to an enhanced homestead food production program improves child hemoglobin, iron and vitamin A status in rural Burkina Faso: A cluster randomized controlled trial. Journal of Nutrition 156(6): 101519. https://doi.org/10.1016/j.tjnut.2026.101519
Country/Region
Burkina Faso
Keywords
Africa; Sub-saharan Africa; Western Africa; Capacity Building; Lipids; Supplements; Food Production; Children; Child Nutrition; Haemoglobin; Iron; Retinol; Randomized Controlled Trials
Project
Agriculture for Nutrition and Health
Record type
Journal Article
